Fmoc-Cit-OH
Product Specifications
UNSPSC Description
Fmoc-Cit-OH (Fmoc-L-Citrulline) is an amino acid derivative with an Fmoc protecting group, which can be used to synthesize a degradable ADC linker composed of a valine-citrulline (Val-Cit) motif[1].
Target Antigen
Amino Acid Derivatives
Type
Peptides
Related Pathways
Others
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/fmoc-cit-oh.html
Purity
99.76
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
NC(NCCC[C@@H](C(O)=O)NC(OCC1C2=CC=CC=C2C3=CC=CC=C31)=O)=O
Molecular Weight
397.42
References & Citations
[1]Pryyma, et al. "Rapid, high-yielding solid-phase synthesis of cathepsin-B cleavable linkers for targeted cancer therapeutics." Bioconjugate Chemistry 31.12 (2020): 2685-2690.
Shipping Conditions
Room Temperature
Storage Conditions
Store at room temperature 3 years
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-W008064/Fmoc-Cit-OH-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-W008064/Fmoc-Cit-OH-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
133174-15-9
Available Sizes
Curated Selection
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