RH1
RH1 (NSC 697726) is a potent bioreductive agent with profound anti-cancer activity in vitro and in vivo.
Product Specifications
CAS Number
221635-42-3
Product Name Alternative
NSC 697726
UNSPSC
12352005
Target
Apoptosis
Type
Reference compound
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/RH1.html
Purity
97.10
Solubility
DMSO : 1.25 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C1C(N2CC2)=C(CO)C(C(N3CC3)=C1C)=O
Molecular Formula
C12H14N2O3
Molecular Weight
234.25
References & Citations
[1]Park MT, et al. The anti-tumour compound, RH1, causes mitochondria-mediated apoptosis by activating c-Jun N-terminal kinase. Br J Pharmacol. 2011 Jun;163 (3) :567-85.|[2]Dehn DL, et al. Development of a new isogenic cell-xenograft system for evaluation of NAD (P) H:quinone oxidoreductase-directed antitumor quinones: evaluation of the activity of RH1. Clin Cancer Res. 2004 May 1;10 (9) :3147-55.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Reference compound1
Clinical Information
Phase 1
Available Sizes
Frequently Asked Questions
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