IQP-0528
IQP-0528 is a highly potent nonnucleoside reverse transcriptase inhibitor (NNRTI) . IQP-0528 shows nanomolar activity against both HIV-1 and HIV-2, with EC50s of 0.2 nM and 100 nM, respectively[1].
Product Specifications
CAS Number
301297-45-0
UNSPSC
12352005
Target
HIV; Reverse Transcriptase
Type
Reference compound
Related Pathways
Anti-infection
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/iqp-0528.html
Concentration
10mM
Purity
99.90
Solubility
DMSO : 25 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C1NC(C(C(C)C)=C(C(C2=CC(C)=CC(C)=C2)=O)N1CC3CC3)=O
Molecular Formula
C20H24N2O3
Molecular Weight
340.42
References & Citations
[1]Su JT, et al. A Dose Ranging Pharmacokinetic Evaluation of IQP-0528 Released from Intravaginal Rings in Non-Human Primates. Pharm Res. 2017;34 (10) :2163-2171.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
HIV-1; HIV-2
Available Sizes
Frequently Asked Questions
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