ULK1-IN-2
ULK1-IN-2 (compound 3s) is a potent ULK1 inhibitor. ULK1-IN-2 shows highest cytotoxic effect against cancer cell lines, with IC50 of 1.94 μM in A549. ULK1-IN-2 can induce apoptosis and simultaneously block autophagy, and can be used to study NSCLC (Non-small cell lung cancer) [1].
Product Specifications
CAS Number
2497409-01-3
UNSPSC
12352005
Target
AMPK; Apoptosis; Autophagy; FAK; ULK
Type
Reference compound
Related Pathways
Apoptosis; Autophagy; Epigenetics; PI3K/Akt/mTOR; Protein Tyrosine Kinase/RTK
Applications
COVID-19-immunoregulation
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ulk1-in-2.html
Concentration
10mM
Purity
98.34
Solubility
DMSO : 33.33 mg/mL (ultrasonic)
Smiles
COC1=C(OC)C(OC)=CC(NC2=NC=C(Br)C(OC3=CC=C([N+]([O-])=O)C=C3F)=N2)=C1
Molecular Formula
C19H16BrFN4O6
Molecular Weight
495.26
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
ULK1
Available Sizes
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
Descyclopropyl Bexagliflozin Carboxylic Acid
