Argadin
Product Specifications
UNSPSC Description
Argadin is a cyclopentapeptide chitinase inhibitor. Argadin inhibits chitinase B (ChiB) with a Ki value of 20 nM. Argadin can be used for the research of fungicid and insecticid[1][2].
Target Antigen
Parasite
Type
Peptides
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/argadin.html
Purity
98.71
Solubility
DMSO : 25 mg/mL (ultrasonic)
Smiles
O=C([C@@H](NC([C@](CCC1)([H])N1C2=O)=O)C3)N([C@@H]3O)[C@H](C(N[C@H](C(N[C@H]2CCCNC(NC(C)=O)=N)=O)CCCC(O)=O)=O)CC4=CN=CN4
Molecular Weight
674.71
References & Citations
[1]Jun Koseki, et al. Molecular Orbital Study of the Formation of Intramolecular Hydrogen Bonding of a Ligand Molecule in a Protein Aromatic Hydrophobic Pocket. Chem Pharm Bull (Tokyo). 2016;64(7):1031-5. |[2]Hiroaki Gouda, et al. Computational analysis of the binding affinities of the natural-product cyclopentapeptides argifin and argadin to chitinase B from Serratia marcescens. Bioorg Med Chem. 2008 Apr 1;16(7):3565-79.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-P3461/Argadin-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-P3461/Argadin-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
289665-92-5
Available Sizes
Curated Selection
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