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Argadin

Argadin is a cyclopentapeptide chitinase inhibitor. Argadin inhibits chitinase B (ChiB) with a Ki value of 20 nM. Argadin can be used for the research of fungicid and insecticid[1][2].

Product Specifications

CAS Number

289665-92-5

UNSPSC

12352209

Target

Parasite

Type

Peptides

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/argadin.html

Purity

98.71

Solubility

DMSO : 25 mg/mL (ultrasonic)

Smiles

O=C([C@@H](NC([C@](CCC1)([H])N1C2=O)=O)C3)N([C@@H]3O)[C@H](C(N[C@H](C(N[C@H]2CCCNC(NC(C)=O)=N)=O)CCCC(O)=O)=O)CC4=CN=CN4

Molecular Formula

C29H42N10O9

Molecular Weight

674.71

References & Citations

[1]Jun Koseki, et al. Molecular Orbital Study of the Formation of Intramolecular Hydrogen Bonding of a Ligand Molecule in a Protein Aromatic Hydrophobic Pocket. Chem Pharm Bull (Tokyo) . 2016;64 (7) :1031-5. |[2]Hiroaki Gouda, et al. Computational analysis of the binding affinities of the natural-product cyclopentapeptides argifin and argadin to chitinase B from Serratia marcescens. Bioorg Med Chem. 2008 Apr 1;16 (7) :3565-79.

Shipping Conditions

Blue Ice

Storage Conditions

-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light)

Scientific Category

Peptides

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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