GT 949
GT 949 is a selective excitatory amino acid transporter-2 (EAAT2) positive allosteric modulator with an EC50 of 0.26 nM[1].
Product Specifications
CAS Number
[460330-27-2]
Product Name Alternative
SC 0030
UNSPSC
12352005
Target
EAAT
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/GT_949.html
Purity
99.55
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
O=C1NC2=C(C=C(OC)C=C2)C=C1C(N3CCN(C4CCCCC4)CC3)C5=NN=NN5CCC6=CC=CC=C6
Molecular Formula
C30H37N7O2
Molecular Weight
527.66
References & Citations
[1]Kortagere S, et al. Identification of Novel Allosteric Modulators of Glutamate Transporter EAAT2. ACS Chem Neurosci. 2018 Mar 21;9 (3) :522-534.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
EAAT2
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
589749 96 Tests
Serum/Glucocorticoid Regulated Kinase 1 (SGK1) BioAssayTM ELISA Kit (Human)
Ask
View Details 
C0005-85 200 µL
CCHCR1, ID (Coiled-coil alpha-helical Rod Protein 1, Alpha-helical Coiled-coil Rod Protein, Putative Gene 8 Protein, Pg8, HCR, C6orf18)
Ask
View Details 
041146-APC 200 µL
RNF40, CT (RNF40, BRE1B, KIAA0661, E3 ubiquitin-protein ligase BRE1B, 95kD retinoblastoma-associated protein, RING finger protein 40) (APC) discontinued
Ask
View Details