GT 949

GT 949 is a selective excitatory amino acid transporter-2 (EAAT2) positive allosteric modulator with an EC50 of 0.26 nM[1].

Product Specifications

CAS Number

[460330-27-2]

Product Name Alternative

SC 0030

UNSPSC

12352005

Target

EAAT

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/GT_949.html

Purity

99.55

Solubility

DMSO : 50 mg/mL (ultrasonic)

Smiles

O=C1NC2=C(C=C(OC)C=C2)C=C1C(N3CCN(C4CCCCC4)CC3)C5=NN=NN5CCC6=CC=CC=C6

Molecular Formula

C30H37N7O2

Molecular Weight

527.66

References & Citations

[1]Kortagere S, et al. Identification of Novel Allosteric Modulators of Glutamate Transporter EAAT2. ACS Chem Neurosci. 2018 Mar 21;9 (3) :522-534.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

EAAT2

Available Sizes

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

NBP2-62210AF488 0.1 mL

Mouse Monoclonal OPAL1 Antibody (OPAL1-01) [Alexa Fluor 488]

Ask

View Details

abx231316 100 µg

Protein CBFA2T3 (CBFA2T3) Antibody

Ask

View Details

MBS6485865-01 0.1 mL

Macrophage Inflammatory Protein 1 alpha (MIP-1a) (MaxLight 650)

Ask

View Details

MBS6485865-02 5x 0.1 mL

Macrophage Inflammatory Protein 1 alpha (MIP-1a) (MaxLight 650)

Ask

View Details

FAB1848N-100UG 100 µg

Human KIR/CD158 Alexa Fluor 700 Antibody (Clone 180704)

Ask

View Details

158182 96 Tests

Tryptase (TPS) BioAssayTM ECL ELISA Kit (Human)

Ask

View Details