GT 949

GT 949 is a selective excitatory amino acid transporter-2 (EAAT2) positive allosteric modulator with an EC50 of 0.26 nM[1].

Product Specifications

CAS Number

[460330-27-2]

Product Name Alternative

SC 0030

UNSPSC

12352005

Target

EAAT

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/GT_949.html

Purity

99.55

Solubility

DMSO : 50 mg/mL (ultrasonic)

Smiles

O=C1NC2=C(C=C(OC)C=C2)C=C1C(N3CCN(C4CCCCC4)CC3)C5=NN=NN5CCC6=CC=CC=C6

Molecular Formula

C30H37N7O2

Molecular Weight

527.66

References & Citations

[1]Kortagere S, et al. Identification of Novel Allosteric Modulators of Glutamate Transporter EAAT2. ACS Chem Neurosci. 2018 Mar 21;9 (3) :522-534.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

EAAT2

Available Sizes

Curated Selection

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