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Pachypodol (Standard)

Pachypodol (Standard) is the analytical standard of Pachypodol. This product is intended for research and analytical applications. Pachypodol is an orally active methoxyflavonoid compound. Pachypodol activates the ERK-dependent Nrf2 pathway and inhibits Apoptosis. Pachypodol exhibits activities such as antioxidant, cytoprotective, anti-inflammatory effects. Pachypodol improves cognition. Pachypodol exerts protective effects against cardiac and liver damage. Pachypodol has anticancer activity against colon cancer[1][2][3][4][5].

Product Specifications

CAS Number

33708-72-4

UNSPSC

12352005

Target

Apoptosis; Keap1-Nrf2; PERK; Reference Standards

Type

Reference Standards

Related Pathways

Apoptosis; Cell Cycle/DNA Damage; NF-κB; Others

Field of Research

Cancer; Metabolic Disease; Neurological Disease; Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/pachypodol-standard.html

Smiles

O=C1C(OC)=C(C2=CC(OC)=C(O)C=C2)OC3=CC(OC)=CC(O)=C13

Molecular Formula

C18H16O7

Molecular Weight

344.32

References & Citations

[1]Kim EK, et al. Pachypodol, a Methoxyflavonoid Isolated from Pogostemon cablin Bentham Exerts Antioxidant and Cytoprotective Effects in HepG2 Cells: Possible Role of ERK-Dependent Nrf2 Activation. Int J Mol Sci. 2019;20 (17) :4082. Published 2019 Aug 21.|[2]Ali HA, et al. Pachypodol, a flavonol from the leaves of Calycopteris floribunda, inhibits the growth of CaCo 2 colon cancer cell line in vitro. Phytother Res. 2008;22 (12) :1684-1687.

Shipping Conditions

Room temperature

Scientific Category

Reference Standards

Frequently Asked Questions

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