Dorsomorphin (dihydrochloride) (GMP)

Dorsomorphin dihydrochloride (GMP) is the GMP level of Dorsomorphin dihydrochloride (HY-13418) . GMP guidelines are used to produce Dorsomorphin dihydrochloride (GMP) . GMP small molecules works appropriately as an auxiliary reagent for cell research manufacture. Dorsomorphin dihydrochloride (GMP) is a potent, selective and ATP-competitive AMPK inhibitor. Dorsomorphin dihydrochloride (GMP) can be used for the research of induced differentiation of pluripotent stem cells (PSCs) [1][2].

Product Specifications

CAS Number

[1219168-18-9]

Product Name Alternative

Compound C (dihydrochloride) (GMP) ; BML-275 (dihydrochloride) (GMP)

UNSPSC

12352005

Target

AMPK

Type

GMP Small Molecules

Related Pathways

Epigenetics; PI3K/Akt/mTOR

Applications

Cancer-Kinase/protease

Field of Research

Cancer; Neurological Disease

Assay Protocol

https://www.medchemexpress.com/dorsomorphin-dihydrochloride-gmp.html

Purity

99.70

Solubility

10 mM in DMSO

Smiles

[H]Cl.[H]Cl.C12=C(C3=CC=NC=C3)C=NN1C=C(C4=CC=C(OCCN5CCCCC5)C=C4)C=N2

Molecular Formula

C24H27Cl2N5O

Molecular Weight

472.41

References & Citations

[1]Fjodorova, Marija, et al. Robust Induction of DARPP32-Expressing GABAergic Striatal Neurons from Human Pluripotent Stem Cells. Methods in molecular biology (Clifton, N.J.) vol. 1780 (2018) : 585-605.|[2]Piragyte, Indre et al. A metabolic interplay coordinated by HLX regulates myeloid differentiation and AML through partly overlapping pathways. Nature communications vol. 9,1 3090. 6 Aug. 2018.