SU5214
SU5214 is a potent VEGFR2 inhibitor extracted from patent US5834504A, SU5214, has IC50s of 14.8 µM (FLK-1) and 36.7 µM (EGFR), respectively[1].
Product Specifications
CAS Number
[186611-04-1]
Product Name Alternative
SU4949
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
VEGFR
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/su5214.html
Purity
98.0
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C1NC2=C(C=CC=C2)/C1=C/C3=CC=CC=C3OC
Molecular Formula
C16H13NO2
Molecular Weight
251.28
Precautions
H302, H315, H319, H335
References & Citations
[1]Tang et al. 3- (2'-halobenzylidenyl) -2-indolinone compounds for the treatment of disease. US5834504A.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
VEGFR2/KDR/Flk-1
Available Sizes
Curated Selection
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