Recombinant Human Collagen alpha-1 protein (COL15A1) (Active)
Product Specifications
Background
Structural protein that stabilizes microvessels and muscle cells, both in heart and in skeletal muscle. {ECO:0000269|PubMed:10049780}.; Restin potently inhibits angiogenesis. {ECO:0000250}.
Product Name Alternative
XV, Related to endostatin, Restin-I, ; Restin-2 Restin-II, ; Restin-3 Restin-III
Gene ID
1306
UniProt
P39059
Target
NYEKPALHLA ALNMPFSGDI RADFQCFKQA RAAGLLSTYR AFLSSHLQDL STIVRKAERY SLPIVNLKGQ VLFNNWDSIF SGHGGQFNMH IPIYSFDGRD IMTDPSWPQK VIWHGSSPHG VRLVDNYCEA WRTADTAVTG LASPLSTGKI LDQKAYSCAN RLIVLCIENS FMTDARK
Purification
>96% as determined by SDS-PAGE and HPLC.
Bioactivity
Fully biologically active when compared to standard. The ED50 as determined by inhibiting the FGF basic-dependent proliferation of HUVEC migration is less than 2.0 ?g, mL in the presence of Anti- Human Endostatin Polyclonal Antibody.
Storage Conditions
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Calculated Molecular Weight
19.8 kDa
Formulation
0.2 μ m filtered PBS, pH 7.4 , lyophilized
Host or Source
E.Coli
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