Tri-GalNAc-COOH

Tri-GalNAc-COOH is an asialoglycoprotein receptor (ASGPR) ligand that can be used for LYsosome TArgeting Chimera (LYTAC) research[1].

Product Specifications

CAS Number

[1953146-81-0]

UNSPSC

12352005

Hazard Statement

H315, H319

Target

LYTACs

Type

Reference compound

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/tri-galnac-cooh.html

Purity

99.0

Solubility

DMSO : 250 mg/mL (ultrasonic)

Smiles

O=C(CCOCCOCCOCCOCCOCCC(O)=O)NC(COCCC(NCCCNC(CCCCO[C@H](O[C@@H]1CO)[C@@H]([C@H]([C@H]1O)O)NC(C)=O)=O)=O)(COCCC(NCCCNC(CCCCO[C@H](O[C@@H]2CO)[C@@H]([C@H]([C@H]2O)O)NC(C)=O)=O)=O)COCCC(NCCCNC(CCCCO[C@H](O[C@@H]3CO)[C@@H]([C@H]([C@H]3O)O)NC(C)=O)=O)=O

Molecular Formula

C75H134N10O35

Molecular Weight

1735.91

Precautions

H315, H319

References & Citations

[1]Yaxian Zhou, et al. Development of Triantennary N-Acetylgalactosamine Conjugates as Degraders for Extracellular Proteins. ACS Cent Sci. 2021 Mar 24;7 (3) :499-506.