Jun12682
Product Specifications
UNSPSC Description
Jun12682 is an inhibitor of SARS-CoV-2 papain-like protease. Jun12682 inhibits PLpro with a Ki value of 37.7 nM. Jun12682 has EC50 value of 1.1 μM in the FlipGFP PLpro assay. Jun12682 has orally activity[1].
Target Antigen
SARS-CoV
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/jun12682.html
Solubility
DMSO : 100 mg/mL (ultrasonic;warming;heat to 60°C)
Smiles
CC1=CC=C(C=C1C(N[C@@H](C2=CC(C3=CN(C)N=C3)=CC(C4=NN(CC)C=C4)=C2)C)=O)OCCN(C)C
Molecular Weight
500.64
References & Citations
[1]Bin Tan, et al. Design of SARS-CoV-2 papain-like protease inhibitor with antiviral efficacy in a mouse model. bioRxiv. 2023.
Shipping Conditions
Room Temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-157403/Jun12682-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-157403/Jun12682-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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