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Mesothelin Antibody / MSLN

Mesothelin is a 40kDa glycosyl-phosphatidylinositol-anchored glycoprotein cleaved from a 69kDa precursor protein. Mesothelin immunoreactivity is high in cancers of the ovary (serous papillary, endometrioid and undifferentiated) and pancreas, with less frequent staining seen in adenocarcinomas of the endometrium, lung and stomach/esophagus. Mesothelin is one of the most sensitive markers for mesothelioma.

Product Specifications

UniProt

Q13421

Reactivity

Human

Immunogen

A portion of amino acids 273-407 from human Mesothelin protein was used as the immunogen for the Mesothelin antibody.

Clonality

Monoclonal

Clone

MSLN/3383

Conjugation

Unconjugated

Purification

Protein G affinity

Dilution

Western blot: 1-2ug/ml

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Notes

For research use only.

Applications Notes

Optimal dilution of the Mesothelin antibody should be determined by the researcher.

Tested Applications

WB

Host or Source

Mouse

Preservative

1 mg/ml in 1X PBS; rAlbumin free, sodium azide free

Isotype

Mouse IgG1, kappa

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