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Hexokinase 1 Antibody / HK1

Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes a ubiquitous form of hexokinase which localizes to the outer membrane of mitochondria. Mutations in this gene have been associated with hemolytic anemia due to hexokinase deficiency. Alternative splicing of this gene results in several transcript variants which encode different isoforms, some of which are tissue-specific.

Product Specifications

UniProt

P19367

Reactivity

Human

Immunogen

A portion of amino acids 1-200 from human HK1 protein was used as the immunogen for the Hexokinase 1 antibody.

Clonality

Monoclonal

Clone

HK1/9504

Conjugation

Unconjugated

Field of Research

Signal Transduction

Purification

Protein G affinity

Dilution

Immunohistochemistry (FFPE) : 1-2ug/ml, Western blot: 2-4ug/ml

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Notes

For research use only.

Applications Notes

Optimal dilution of the Hexokinase 1 antibody should be determined by the researcher.

Tested Applications

IHC-P, WB

Host or Source

Mouse

Preservative

0.2 mg/ml in 1X PBS with 0.1 mg/ml rAlbumin, 0.05% sodium azide

Isotype

Mouse IgG2b, kappa

Available Sizes

Frequently Asked Questions

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