17-beta-HSD 13 Antibody / HSD17B13
Hydroxysteroid 17-beta dehydrogenase 13 (HSD17B13, 17-beta-HSD 13) is an enzyme in the liver that is associated with lipid droplets. It is encoded by the HSD17B13 gene in humans. HSD17B13 levels increase in patients with non-alcoholic fatty liver disease (NAFLD) and can enhance lipogenesis. However, some studies have shown that loss-of-function variants in HSD17B13 may protect against the progression of NAFLD to non-alcoholic steatohepatitis, fibrosis, and hepatocellular carcinoma.
Product Specifications
UniProt
Q7Z5P4
Reactivity
Human
Immunogen
A portion of amino acids 1-200 of the human protein was used as the immunogen for the 17-beta-HSD 13 antibody.
Clonality
Monoclonal
Clone
HSD17B13/13104
Conjugation
Unconjugated
Field of Research
Metabolism Research
Purification
Protein G affinity
Dilution
Immunohistochemistry (FFPE) : 1-2ug/ml
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Applications Notes
Optimal dilution of the 17-beta-HSD 13 antibody should be determined by the researcher.
Tested Applications
IHC-P
Host or Source
Mouse
Preservative
1 mg/ml in 1X PBS; rAlbumin free, sodium azide free
Isotype
Mouse IgG2b, kappa
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