Hydroxysteroid 17-beta dehydrogenase 13 Antibody / HSD17B13
Hydroxysteroid 17-beta dehydrogenase 13 (HSD17B13) is an engyme in the liver that is associated with lipid droplets. It is encoded by the HSD17B13 gene in humans. HSD17B13 levels increase in patients with non-alcoholic fatty liver disease (NAFLD) and can enhance lipogenesis. However, some studies have shown that loss-of-function variants in HSD17B13 may protect against the progression of NAFLD to non-alcoholic steatohepatitis, fibrosis, and hepatocellular carcinoma.
Product Specifications
UniProt
Q7Z5P4
Reactivity
Human
Immunogen
A portion of amino acids 1-200 of the human protein was used as the immunogen for the Hydroxysteroid 17-beta dehydrogenase 13 antibody.
Clonality
Monoclonal
Clone
HSD17B13/13108
Conjugation
Unconjugated
Field of Research
Metabolism Research
Purification
Protein G affinity
Dilution
Immunohistochemistry (FFPE) : 1-2ug/ml
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Applications Notes
Optimal dilution of the Hydroxysteroid 17-beta dehydrogenase 13 antibody should be determined by the researcher.
Tested Applications
IHC-P
Host or Source
Mouse
Preservative
1 mg/ml in 1X PBS; rAlbumin free, sodium azide free
Isotype
Mouse IgG2b, kappa
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