Recombinant CA9 Antibody / Carbonic anhydrase 9
Recognizes a glycoprotein of ~200kDa, identified as carbonic anhydrase IX (CAIX/gp200) .In normal kidney, gp200 is localized along the brush border of the pars convoluta and pars recta segments of the proximal tubule, as well as focally along the luminal surface of Bowman's capsule adjoining the outgoing proximal tubule. Reportedly, gp200 is expressed by 93% of primary and 84% of metastatic renal cell carcinomas. This MAb may be useful in the investigations of carcinomas of proximal nephrogenic differentiation especially those showing tubular differentiation.
Product Specifications
UniProt
Q16790
Reactivity
Human
Immunogen
Clonality
Recombinant
Clone
RCA9/9937
Conjugation
Unconjugated
Purification
Protein G affinity
Dilution
Immunohistochemistry (FFPE) : 1-2ug/ml, Western blot: 2-4ug/ml
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Applications Notes
Optimal dilution of the recombinant CA9 antibody should be determined by the researcher.
Tested Applications
IHC-P, WB
Host or Source
Mouse
Preservative
1 mg/ml in 1X PBS; rAlbumin free, sodium azide free
Isotype
Mouse IgG2b, kappa
Frequently Asked Questions
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