HPV-16 Antibody / E6 protein
Reacts with E6 protein of human papilloma virus type 16 (HPV-16) . Infection with specific types of HPV has been associated with an increased risk of developing cervical neoplasia. HPV types 6 and 11 have been associated with relatively benign diseases such as genital warts but types 16 and 18 are strongly associated with cervical, vaginal, and vulvar malignancies. The antibody reacts very strongly with formalin-fixed, paraffin-embedded tissues containing HPV-16.
Product Specifications
Reactivity
Human
Immunogen
HPV-16 E6 peptide MHQKRTAMFQDPPQERPRKLPQLC was used as the immmunogen for the HPV-16 antibody.
Clonality
Monoclonal
Clone
4B12
Conjugation
Unconjugated
Field of Research
Infectious Disease & Virology; Cancer Biology
Purification
Protein G affinity
Dilution
Immunohistochemistry (FFPE) : 1-2ug/ml
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Applications Notes
Optimal dilution of the HPV-16 antibody should be determined by the researcher.
Tested Applications
IHC-P
Host or Source
Mouse
Preservative
1 mg/ml in 1X PBS; rAlbumin free, sodium azide free
Isotype
Mouse IgG2a, kappa
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