Apolipoprotein E from Human Plasma

<strong>Apolipoprotein E from Human Plasma</strong>_x000D_ <strong>Catalog number:</strong> B2014475_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 50 ug_x000D_ <strong>Molecular Weight or Concentration:</strong> 34 kDa_x000D_ <strong>Supplied as:</strong> Solution_x000D_ <strong>Applications:</strong> molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> -20°C_x000D_ <strong>Keywords:</strong> Apo E_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Kemp SB, Carpenter ES, Steele NG, Donahue KL, Nwosu ZC, Pacheco A, Velez-Delgado A, Menjivar RE, Lima F, The S, Espinoza CE, Brown K, Long D, Lyssiotis CA, Rao A, Zhang Y, Pasca di Magliano M, Crawford HC. Apolipoprotein E Promotes Immune Suppression in Pancreatic Cancer through NF-κB-Mediated Production of CXCL1 Cancer Res. 2021 Aug 15;81(16):4305-4318._x000D_ 2: Alagarsamy J, Jaeschke A, Hui DY. Apolipoprotein E in Cardiometabolic and Neurological Health and Diseases Int J Mol Sci. 2022 Aug 31;23(17):9892._x000D_ 3: Rasmussen KL. Plasma levels of apolipoprotein E, APOE genotype and risk of dementia and ischemic heart disease: A review Atherosclerosis. 2016 Dec;255:145-155._x000D_ 4: Palmqvist S, Tideman P, Cullen N, Zetterberg H, Blennow K; Alzheimer’s Disease Neuroimaging Initiative; Dage JL, Stomrud E, Janelidze S, Mattsson-Carlgren N, Hansson O. Prediction of future Alzheimer's disease dementia using plasma phospho-tau combined with other accessible measures Nat Med. 2021 Jun;27(6):1034-1042._x000D_ 5: Shinohata R, Shiga Y, Miura SI, Hirohata S, Shibakura M, Ueno-Iio T, Watanabe S, Arao Y, Usui S. Low plasma apolipoprotein E-rich high-density lipoprotein levels in patients with metabolic syndrome Clin Chim Acta. 2020 Nov;510:531-536._x000D_ 6: Fortea J, Vilaplana E, Carmona-Iragui M, Benejam B, Videla L, Barroeta I, Fernández S, Altuna M, Pegueroles J, Montal V, Valldeneu S, Giménez S, González-Ortiz S, Muñoz L, Estellés T, Illán-Gala I, Belbin O, Camacho V, Wilson LR, Annus T, Osorio RS, Videla S, Lehmann S, Holland AJ, Alcolea D, Clarimón J, Zaman SH, Blesa R, Lleó A. Clinical and biomarker changes of Alzheimer's disease in adults with Down syndrome: a cross-sectional study Lancet. 2020 Jun 27;395(10242):1988-1997._x000D_ 7: Zhang Z, Guan J, Jiang Z, Yang Y, Liu J, Hua W, Mao Y, Li C, Lu W, Qian J, Zhan C. Brain-targeted drug delivery by manipulating protein corona functions Nat Commun. 2019 Aug 8;10(1):3561._x000D_ 8: Li L, Li R, Zacharek A, Wang F, Landschoot-Ward J, Chopp M, Chen J, Cui X. ABCA1/ApoE/HDL Signaling Pathway Facilitates Myelination and Oligodendrogenesis after Stroke Int J Mol Sci. 2020 Jun 19;21(12):4369._x000D_ 9: Rasmussen KL, Tybjærg-Hansen A, Nordestgaard BG, Frikke-Schmidt R. Plasma levels of apolipoprotein E and risk of ischemic heart disease in the general population Atherosclerosis. 2016 Mar;246:63-70._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/31071995">10: Tsiolaki PL, Katsafana AD, Baltoumas FA, Louros NN, Iconomidou VA. Hidden Aggregation Hot-Spots on Human Apolipoprotein E: A Structural Study Int J Mol Sci. 2019 May 8;20(9):2274. </a>_x000D_ _x000D_ <strong>Products Related to Apolipoprotein E from Human Plasma can be found at</strong> <a href="https://moleculardepot.com/product-category/Proteins/"> Proteins</a>