hMAO-B/MB-COMT-IN-1
Product Specifications
UNSPSC Description
hMAO-B/MB-COMT-IN-1 is a dual MAO-B/MB-COMT inhibitor (IC50s: 2.5 μΜ for hMAO-B, 3.84 μΜ for MB-COMT). hMAO-B/MB-COMT-IN-1 protects cells against oxidative damage. hMAO-B/MB-COMT-IN-1 can be used in the research of neurodegeneration disease, such as Parkinson’s Disease (PD)[1].
Target Antigen
COMT; Monoamine Oxidase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease;Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/hmao-b-mb-comt-in-1.html
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
OC1=C(C=CC(/C=C/C=C/C(N2CCCCC2)=O)=C1)O
Molecular Weight
273.33
References & Citations
[1]Daniel Chavarria, et al. Boosting caffeic acid performance as antioxidant and monoamine oxidase B/catechol-O-methyltransferase inhibitor. Eur J Med Chem. 2022 Sep 8;243:114740.
Shipping Conditions
Room Temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-151388/hMAO-B-MB-COMT-IN-1-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-151388/hMAO-B-MB-COMT-IN-1-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
254974-70-4
Available Sizes
Curated Selection
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