Nicodicosapent
Nicodicosapent is a fatty acid niacin conjugate that is also an inhibitor of the sterol regulatory element binding protein (SREBP), a key regulator of cholesterol metabolism proteins such as PCSK9, HMG-CoA reductase, ATP citrate lyase, and NPC1L1.
Product Specifications
CAS Number
1269181-69-2
UNSPSC
12352005
Target
Autophagy; Fatty Acid Synthase (FASN)
Type
Reference compound
Related Pathways
Autophagy; Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/Nicodicosapent.html
Purity
99.79
Solubility
DMSO : 100 mg/mL (ultrasonic) |Ethanol : 3.33 mg/mL (ultrasonic)
Smiles
O=C(C1=CC=CN=C1)NCCNC(CCC/C=C\C/C=C\C/C=C\C/C=C\C/C=C\CC)=O
Molecular Formula
C28H39N3O2
Molecular Weight
449.63
References & Citations
[1]Vu CB, et al. Synthesis and Characterization of Fatty Acid Conjugates of Niacin and Salicylic Acid. J Med Chem. 2016 Feb 11;59 (3) :1217-31.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, stored under nitrogen)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
HSV1 (Herpes Simplex Virus Type I) (HSV1/1934), CF568 conjugate, 0.1mg/mL
![Syntaxin 1a Recombinant Rabbit Monoclonal Antibody [JE54-37]](https://cdn.genprice.uk/products/992/68dd1c90061270361ea82bee/imageurl/et7110-68.webp)
Syntaxin 1a Recombinant Rabbit Monoclonal Antibody [JE54-37]
