Dehydrojuncusol
Dehydrojuncusol, a potent HCV inhibitor, targets HCV NS5A and is able to inhibit RNA replication of replicons harboring resistance mutations to anti-NS5A direct-acting antivirals. Dehydrojuncusol significantly inhibits HCV infection when added after virus inoculation of HCV genotype 2a (EC50=1.35 μM) [1].
Product Specifications
CAS Number
117824-04-1
UNSPSC
12352005
Target
HCV; HCV Protease
Type
Natural Products
Related Pathways
Anti-infection; Metabolic Enzyme/Protease
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/dehydrojuncusol.html
Solubility
10 mM in DMSO
Smiles
OC1=CC=C2C3=C(C=C)C(C)=C(O)C=C3C=CC2=C1C
Molecular Formula
C18H16O2
Molecular Weight
264.32
References & Citations
[1]Sahuc ME, et al. Dehydrojuncusol, a Natural Phenanthrene Compound Extracted from Juncus maritimus, Is a New Inhibitor of Hepatitis C Virus RNA Replication. J Virol. 2019;93 (10) :e02009-18. Published 2019 May 1.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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