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KBH-A42

KBH-A42 is a novel histone deacetylase (HDAC) inhibitor with significant anti-inflammatory properties. KBH-A42 against TNF-α and NO production with IC50 values of 1.10 and 2.71 µM, respectively, in the LPS-induced murine macrophage RAW 264.7 cells[1].

Product Specifications

CAS Number

798543-50-7

UNSPSC

12352005

Target

HDAC

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage; Epigenetics

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/kbh-a42.html

Smiles

O=C(CCC1=CCCN(C1=O)CCCC2=CC=CC=C2)NO

Molecular Formula

C17H22N2O3

Molecular Weight

302.37

References & Citations

[1]Yongseok Choi, et al. Histone deacetylase inhibitor KBH-A42 inhibits cytokine production in RAW 264.7 macrophage cells and in vivo endotoxemia model. Experimental & Molecular Medicine. 2008, 40, 574-581.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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