(Rac) -AMG 628
(Rac) -AMG 628 is the racemate of AMG 628, a potent TRPV1 antagonist with an IC50 of 3.7nM. AMG 628 can be used in chronic pain research[1].
Product Specifications
CAS Number
862269-73-6
UNSPSC
12352005
Target
TRP Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/rac-amg-628.html
Smiles
CC(NC1=NC2=C(OC3=NC=NC(N4CCN(C(C5=CC=C(F)C=C5)C)CC4)=C3)C=CC=C2S1)=O
Molecular Formula
C25H25FN6O2S
Molecular Weight
492.57
References & Citations
[1]Thiel OR, et al. Practical synthesis of a vanilloid receptor-1 antagonist. J Org Chem. 2008 May 2;73 (9) :3508-15.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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