Mevalonic acid (lithium salt)
Product Specifications
UNSPSC Description
Mevalonic acid (MVA) lithium salt is a precursor substance of the mevalonate pathway, which is essential for cell growth and proliferation. Mevalonic acid lithium salt is effective in inhibiting Simvastatin (HY-17502)-induced decrease in C2C12 cell viability in vitro. Mevalonic acid lithium salt can be used in studies of myopathy and heart failure[1][2].
Target Antigen
Endogenous Metabolite
Type
Natural Products
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Metabolic Disease; Neurological Disease; Cardiovascular Disease; Cancer
Assay Protocol
https://www.medchemexpress.com/mevalonic-acid-lithium-salt.html
Purity
99.80
Solubility
DMSO : 50 mg/mL (ultrasonic)|H2O : 100 mg/mL (ultrasonic)
Smiles
O=C(O[Li])CC(C)(O)CCO
Molecular Weight
154.09
References & Citations
[1]Moschetti A, et al. Coenzyme Q nanodisks counteract the effect of statins on C2C12 myotubes. Nanomedicine. 2021 Oct;37:102439.|[2]Soma MR, et al. Cholesterol and mevalonic acid modulation in cell metabolism and multiplication. Toxicol Lett. 1992 Dec;64-65 Spec No:1-15. Acta Pharm Sin B. 2023 Apr 17.|Acta Pharmacol Sin. 2021 Feb 19.|Biochim Biophys Acta Mol Cell Biol Lipids. 2022 Aug 16;159217.|Cell Biosci. 2021 Oct 9;11(1):179.|Life Sci Alliance. 2022 Jan 4;5(3):e202101256.|Nature. 2024 Dec 18.|Biochem Biophys Res Commun. 2020 Feb 19;522(4):862-868.|Biomedicines. 2022, 10(10), 2489.|Drugs R D. 2023 Oct 17.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-113071A/Mevalonic-acid-lithium-salt-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-113071A/Mevalonic-acid-lithium-salt-SDS-MedChemExpress.pdf
Clinical Information
Phase 3
CAS Number
2618458-93-6
Available Sizes
Curated Selection
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