Cefpiramide

Cefpiramide (SM-1652) free acid is a semisynthetic cephalosporin with broad-spectrum antibacterial activity. Cefpiramide free acid shows strong antibacterial effect on both gram-positive bacteria and gram-negative bacteria. Cefpiramide free acid is moderately susceptible to β-lactamase[1][2].

Product Specifications

CAS Number

[70797-11-4]

Product Name Alternative

SM-1652 (free acid) ; Wy-44635 (free acid)

UNSPSC

12352005

Hazard Statement

H302, H312, H332

Target

Antibiotic; Bacterial; Beta-lactamase

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/cefpiramide.html

Purity

99.27

Solubility

DMSO : 125 mg/mL (ultrasonic)

Smiles

O=C(C(N12)=C(CSC3=NN=NN3C)CS[C@]2([H])[C@H](NC([C@H](NC(C4=C(O)C=C(C)N=C4)=O)C5=CC=C(O)C=C5)=O)C1=O)O

Molecular Formula

C25H24N8O7S2

Molecular Weight

612.64

Precautions

H302, H312, H332

References & Citations

[1]Barry AL, et al. Cefpiramide: comparative in-vitro activity and beta-lactamase stability. J Antimicrob Chemother. 1985 Sep;16 (3) :315-25. |[2]Sato K, et al. Pharmacokinetics and bacteriological efficacies of apalcillin and cefpiramide in experimental pneumococcal meningitis. Antimicrob Agents Chemother. 1984 Oct;26 (4) :578-9.