AP30663

AP30663 is a KCa2 channel inhibitor that can be used for the study of atrial fibrillation[1].

Product Specifications

UNSPSC

12352005

Target

Potassium Channel

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/ap30663.html

Concentration

10mM

Purity

99.99

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C(N(CC#N)C)C[C@@H](NC1=NC2=CC=CC=C2N1)C3=CC=CC(C(F)(F)F)=C3

Molecular Formula

C20H18F3N5O

Molecular Weight

401.39

References & Citations

[1]Holst A G, Tomcsányi J, Vestbjerg B, et al. Inhibition of the KCa2 potassium channel in atrial fibrillation: a randomized phase 2 trial[J]. Nature Medicine, 2023: 1-6.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

Phase 2

Available Sizes

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

TL500098V 500 µL Each

Anxa3 Mouse shRNA Lentiviral Particle (Locus ID 11745)

Ask

View Details

NBP3-11275 50 µg

Rabbit Polyclonal ATP7A Antibody

Ask

View Details

bs-6033R-APC 100 µL

Contactin 3 Polyclonal Antibody, APC Conjugated

Ask

View Details

LH17268V 100 µg

VPS41 (NM_080631) Human Over-expression Lysate

Ask

View Details

NBP3-05850AF700 0.1 mL

Rabbit Polyclonal COX4-I1 Antibody [Alexa Fluor 700]

Ask

View Details