AP30663
AP30663 is a KCa2 channel inhibitor that can be used for the study of atrial fibrillation[1].
Product Specifications
UNSPSC
12352005
Target
Potassium Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/ap30663.html
Concentration
10mM
Purity
99.99
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(N(CC#N)C)C[C@@H](NC1=NC2=CC=CC=C2N1)C3=CC=CC(C(F)(F)F)=C3
Molecular Formula
C20H18F3N5O
Molecular Weight
401.39
References & Citations
[1]Holst A G, Tomcsányi J, Vestbjerg B, et al. Inhibition of the KCa2 potassium channel in atrial fibrillation: a randomized phase 2 trial[J]. Nature Medicine, 2023: 1-6.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 2
Available Sizes
Curated Selection
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