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AP30663

Product Specifications

UNSPSC Description

AP30663 is a KCa2 channel inhibitor that can be used for the study of atrial fibrillation[1].

Target Antigen

Potassium Channel

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/ap30663.html

Solubility

10 mM in DMSO

Smiles

O=C(N(CC#N)C)C[C@@H](NC1=NC2=CC=CC=C2N1)C3=CC=CC(C(F)(F)F)=C3

Molecular Weight

401.39

References & Citations

[1]Holst A G, Tomcsányi J, Vestbjerg B, et al. Inhibition of the KCa2 potassium channel in atrial fibrillation: a randomized phase 2 trial[J]. Nature Medicine, 2023: 1-6.

Shipping Conditions

Room Temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-157557/AP30663-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-157557/AP30663-SDS-MedChemExpress.pdf

Clinical Information

Phase 2

Available Sizes

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