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Eleutheroside B1

Product Specifications

UNSPSC Description

Eleutheroside B1, a coumarin compound, has a wide spectrum of anti-human influenza virus efficacy, with an IC50?value of 64-125?μg/ml. Eleutheroside B1 mediates its anti-influenza activity through POLR2A and N-glycosylation. Eleutheroside B1 inhibits the mRNA expression of several chemokine genes and the influenza nucleoprotein (NP) gene, and exhibits low cytotoxicity. Antiviral and anti-inflammatory activities[1].

Target Antigen

Influenza Virus

Type

Natural Products

Related Pathways

Anti-infection

Field of Research

Infection; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/eleutheroside-b1.html

Smiles

O=C1C=CC2=CC(OC)=C(O[C@@H]3[C@@H]([C@H]([C@@H]([C@@H](CO)O3)O)O)O)C(OC)=C2O1

Molecular Weight

384.33

References & Citations

[1]Yan W, et al. Eleutheroside B1 mediates its anti-influenza activity through POLR2A and N-glycosylation.Int J Mol Med. 2018 Nov;42(5):2776-2792.

Shipping Conditions

Room Temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-135646/Eleutheroside-B1-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-135646/Eleutheroside-B1-SDS-MedChemExpress.pdf

CAS Number

16845-16-2

Available Sizes

Curated Selection

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