TNO211
TNO211 (Dabcyl-GABA-Pro-Gln-Gly-Leu-Glu (EDANS) -Ala-Lys-NH2) is a fluorogenic substrate, containing the MMP cleavable Gly-Leu bond and EDANS/Dabcyl as fluorophore/quencer combination. TNO211 can specifically detect MMP activity (Ex/Em = 340/485 nm) [1].
Product Specifications
CAS Number
193475-71-7
Product Name Alternative
Dabcyl-GABA-Pro-Gln-Gly-Leu-Glu (EDANS) -Ala-Lys-NH2
UNSPSC
12352209
Target
Fluorescent Dye; MMP
Type
Peptides
Related Pathways
Metabolic Enzyme/Protease; Others
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/tno211.html
Solubility
10 mM in DMSO
Smiles
O=S(O)(C1=CC=CC2=C1C=CC=C2NCCNC(CC[C@@H](C(N[C@@H](C)C(N[C@H](C(N)=O)CCCCN)=O)=O)NC([C@H](CC(C)C)NC(CNC([C@H](CCC(N)=O)NC([C@H]3N(CCC3)C(CCCNC(C4=CC=C(C=C4)/N=N/C5=CC=C(C=C5)N(C)C)=O)=O)=O)=O)=O)=O)=O)=O
Molecular Formula
C63H88N16O14S
Molecular Weight
1325.54
References & Citations
[1]Beekman B, et al. Convenient fluorometric assay for matrix metalloproteinase activity and its application in biological media. FEBS Lett. 1996 Jul 22;390 (2) :221-5.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
OM625384 96 Strip Well
Bovine G Antigen Family D Member 4 (XAGE3) ELISA Kit
Sign In for Pricing
View Details 
MBS2156564-01 96 Tests
Neuropeptide Y (NPY) Magnetic Fluorescence Assay Kit
Sign In for Pricing
View Details MBS2156564-02 5x 96 Tests
Neuropeptide Y (NPY) Magnetic Fluorescence Assay Kit
Sign In for Pricing
View Details MBS2156564-03 10x 96 Tests
Neuropeptide Y (NPY) Magnetic Fluorescence Assay Kit
Sign In for Pricing
View Details