TNO211
TNO211 (Dabcyl-GABA-Pro-Gln-Gly-Leu-Glu (EDANS) -Ala-Lys-NH2) is a fluorogenic substrate, containing the MMP cleavable Gly-Leu bond and EDANS/Dabcyl as fluorophore/quencer combination. TNO211 can specifically detect MMP activity (Ex/Em = 340/485 nm) [1].
Product Specifications
CAS Number
193475-71-7
Product Name Alternative
Dabcyl-GABA-Pro-Gln-Gly-Leu-Glu (EDANS) -Ala-Lys-NH2
UNSPSC
12352209
Target
Fluorescent Dye; MMP
Type
Peptides
Related Pathways
Metabolic Enzyme/Protease; Others
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/tno211.html
Solubility
10 mM in DMSO
Smiles
O=S(O)(C1=CC=CC2=C1C=CC=C2NCCNC(CC[C@@H](C(N[C@@H](C)C(N[C@H](C(N)=O)CCCCN)=O)=O)NC([C@H](CC(C)C)NC(CNC([C@H](CCC(N)=O)NC([C@H]3N(CCC3)C(CCCNC(C4=CC=C(C=C4)/N=N/C5=CC=C(C=C5)N(C)C)=O)=O)=O)=O)=O)=O)=O)=O
Molecular Formula
C63H88N16O14S
Molecular Weight
1325.54
References & Citations
[1]Beekman B, et al. Convenient fluorometric assay for matrix metalloproteinase activity and its application in biological media. FEBS Lett. 1996 Jul 22;390 (2) :221-5.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
Frequently Asked Questions
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