PROTAC Bcl-xL ligand-1
PROTAC Bcl-xL ligand-1 is a ligand for Bcl-xL that can be used in the synthesis of PROTACs[1].
Product Specifications
CAS Number
3029365-95-2
UNSPSC
12352005
Target
Bcl-2 Family; Ligands for Target Protein for PROTAC
Type
Reference compound
Related Pathways
Apoptosis; PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/protac-bcl-xl-ligand-1.html
Purity
99.06
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(C1=C(CCCOC2=CC=C(I)C=C2)SC(N3CCC4=C(C(C(NC5=NC6=CC=CC=C6S5)=O)=CC=C4)C3)=N1)OCC
Molecular Formula
C32H29IN4O4S2
Molecular Weight
724.63
References & Citations
[1]Chun-Wa Chung, et al. Structural Insights into PROTAC-Mediated Degradation of Bcl-xL. ACS Chem Biol. 2020 Sep 18;15 (9) :2316-2323.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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