Ethyl trans-caffeate
Ethyl trans-caffeate is the trans form of Ethyl Caffeate (HY-N6966) . Ethyl Caffeate is a natural phenolic compound isolated from Bidens pilosa. Ethyl caffeate suppresses NF-κB activation and its downstream inflammatory mediators, inducible nitric oxide synthase (iNOS), cyclooxygenase-2 (COX-2), and prostaglandin E2 (PGE2) in vitro or in mouse skin[1].
Product Specifications
CAS Number
[66648-50-8]
UNSPSC
12352005
Hazard Statement
H302
Target
Others
Type
Natural Products
Related Pathways
Others
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/ethyl-trans-caffeate.html
Purity
98.0
Solubility
DMSO : ≥ 100 mg/mL
Smiles
O=C(/C=C/C1=CC=C(C(O)=C1)O)OCC
Molecular Formula
C11H12O4
Molecular Weight
208.21
Precautions
H302
References & Citations
[1]Chiang YM, et al. Ethyl caffeate suppresses NF-kappaB activation and its downstream inflammatory mediators, iNOS, COX-2, and PGE2 in vitro or in mouse skin. Br J Pharmacol. 2005 Oct;146 (3) :352-63.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, protect from light)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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