Apoptosis, Others Antibody
VGL101 is a human IgG1 monoclonal antibody (mAb) that targets TREM-2. It acts as a pSYK agonist with an EC50 of 0.77 nM. Under ALSP pathological conditions, VGL101 enhances the survival of microglia and monocyte-derived macrophages, inhibits apoptosis, and aids in restoring cell morphology to resemble the normal activated CSF1R state. It is applicable in leukoencephalopathy research. Recommended isotype control: Human IgG1 kappa, Isotype Control.
Product Specifications
Target
Apoptosis, Others
Clonality
Monoclonal
Conjugation
Unconjugated
Field of Research
Cell Biology
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
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