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AMT-562 Antibody

AMT-562 is an antibody-drug conjugate (ADC) composed of a novel anti-HER3 antibody, Ab562, linked to the linker Mc-VC-PAB and the topoisomerase I inhibitor, Exatecan. The ADC's toxic component and linker are represented as MC-VA-PAB-Exatecan. AMT-562 can induce apoptosis and exhibits antitumor activity against pancreatic, esophageal, and gastric cancers.

Product Specifications

Target

Antibody-Drug Conjugates (ADCs), Topoisomerase, EGFR, Apoptosis

Clonality

Polyclonal

Conjugation

Unconjugated

Field of Research

Cardiovascular Research, Cell Biology, Molecular Biology, Signal Transduction

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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