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TNF Antibody

TRX-518 is a humanized agonist antibody targeting the glucocorticoid-induced tumor necrosis factor receptor (GITR) . It specifically targets GITR+ regulatory T cells (Tregs) and CD45RA−Foxp3+ effector Tregs (eTregs) within regulatory T cells, effectively reducing the number of Tregs in circulation and within tumors.

Product Specifications

Target

TNF

Conjugation

Unconjugated

Field of Research

Cell Biology, Immunology & Inflammation

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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