AGS-16C3F Antibody
AGS-16C3F is an antibody-drug conjugate (ADC) targeting ENPP3 (also known as CD203c) . This product consists of a humanized IgG1 monoclonal antibody against ENPP3 conjugated to the microtubule inhibitor monomethyl auristatin F (MMAF) via a non-cleavable linker. AGS-16C3F functions by specifically binding to ENPP3 on the surface of tumor cells, undergoing internalization, and releasing MMAF intracellularly to induce cell cycle arrest and apoptosis. It exhibits potent anti-tumor and anti-proliferative activity in ENPP3-expressing metastatic renal cell carcinoma (mRCC) and systemic mastocytosis.
Product Specifications
Target
Others
Clonality
Monoclonal
Conjugation
Unconjugated
Field of Research
Metabolism Research
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Available Sizes
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
Inversin (INVS) (NM_183245) Human Over-expression Lysate
