PTIO

PTIO is a specific scavenger of NO and redox mediator. PTIO reacts with •NO to form the corresponding imino nitroxides and •NO2. PTIO enhances organic contaminants oxidation by permanganate[1][2][3].

Product Specifications

CAS Number

[18390-00-6]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Biochemical Assay Reagents; NO Synthase

Type

Reference compound

Related Pathways

Immunology/Inflammation; Others

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/ptio.html

Purity

99.80

Solubility

DMSO : 166.67 mg/mL (ultrasonic)

Smiles

[O]N1C(C)(C)C(C)(C)[N+]([O-])=C1C2=CC=CC=C2

Molecular Formula

C13H17N2O2

Molecular Weight

233.29

Precautions

H302, H315, H319, H335

References & Citations

[1]Goldstein S, et al. Reactions of PTIO and carboxy-PTIO with *NO, *NO2, and O2-*. J Biol Chem. 2003;278 (51) :50949-50955.|[2]Xia JL , et al. Putrescine regulates nitric oxide accumulation in Ganoderma lucidum partly by influencing cellular glutamine levels under heat stress. Microbiol Res. 2020;239:126521.|[3]Zhao L, et al. PTIO as a redox mediator to enhance organic contaminants oxidation by permanganate. Water Res. 2023 Oct 1;244:120500.