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Fmoc-Gly-NH-CH2-O-CH2-Cbz

Fmoc-Gly-NH-CH2-O-CH2-Cbz is a PROTAC linker and a maleimide-GGFG peptide linker. Fmoc-Gly-NH-CH2-O-CH2-Cbz can be used in the synthesis of the Deruxtecan[1].

Product Specifications

CAS Number

[1599440-07-9]

UNSPSC

12352005

Hazard Statement

H302, H315, H319

Target

PROTAC Linkers

Type

Reference compound

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/fmoc-gly-nh-ch2-o-ch2-cbz.html

Purity

98.47

Solubility

10 mM in DMSO

Smiles

O=C(NCC(NCOCC(OCC1=CC=CC=C1)=O)=O)OCC2C3=C(C4=C2C=CC=C4)C=CC=C3

Molecular Formula

C27H26N2O6

Molecular Weight

474.51

Precautions

H302, H315, H319

References & Citations

[1]NOGUCHI, Shigeru, et al. Method for selectively manufacturing antibody-drug conjugate. WO2017002776A1.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, sealed storage, away from moisture)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

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