Fmoc-Gly-NH-CH2-O-CH2-Cbz
Fmoc-Gly-NH-CH2-O-CH2-Cbz is a PROTAC linker and a maleimide-GGFG peptide linker. Fmoc-Gly-NH-CH2-O-CH2-Cbz can be used in the synthesis of the Deruxtecan[1].
Product Specifications
CAS Number
[1599440-07-9]
UNSPSC
12352005
Hazard Statement
H302, H315, H319
Target
PROTAC Linkers
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/fmoc-gly-nh-ch2-o-ch2-cbz.html
Purity
98.47
Solubility
10 mM in DMSO
Smiles
O=C(NCC(NCOCC(OCC1=CC=CC=C1)=O)=O)OCC2C3=C(C4=C2C=CC=C4)C=CC=C3
Molecular Formula
C27H26N2O6
Molecular Weight
474.51
Precautions
H302, H315, H319
References & Citations
[1]NOGUCHI, Shigeru, et al. Method for selectively manufacturing antibody-drug conjugate. WO2017002776A1.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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