SKF-75670 (hydrobromide)
SKF-75670 hydrochloride is a Dopamine D1 receptor partial agonist. SKF-75670 hydrochloride is also a Cocaine antagonist[1][2][3].
Product Specifications
CAS Number
[62717-63-9]
UNSPSC
12352005
Target
Dopamine Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/skf-75670-hydrobromide.html
Concentration
10mM
Purity
99.83
Solubility
DMSO : 40 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
CN1CCC2=CC(O)=C(O)C=C2C(C3=CC=CC=C3)C1.Br
Molecular Formula
C17H20BrNO2
Molecular Weight
350.25
References & Citations
[1]Rosenzweig-Lipson S, et al. Dopamine D1 receptor involvement in the discriminative-stimulus effects of SKF 81297 in squirrel monkeys. J Pharmacol Exp Ther. 1993 Nov;267 (2) :765-75. |[2]Gnanalingham KK, et al. Differential anti-parkinsonian effects of benzazepine D1 dopamine agonists with varying efficacies in the MPTP-treated common marmoset. Psychopharmacology (Berl) . 1995 Feb;117 (3) :275-86. |[3]Spealman RD, et al. Differential modulation of behavioral effects of cocaine by low- and high-efficacy D1 agonists. Psychopharmacology (Berl) . 1997 Oct;133 (3) :283-92.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, stored under nitrogen, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
D1 Receptor
Available Sizes
Curated Selection
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