Benzyl benzoate

Benzyl benzoate (Phenylmethyl benzoate) is an orally active anti-scabies agent, acaricide (EC50= 0.06 g/m2) and fungicide. Benzyl benzoate is an angiotensin II (Ang II) inhibitor with antihypertensive effects. Benzyl benzoate can be used in perfumes, pharmaceuticals and the food industry[1][2][3][4][5].

Product Specifications

CAS Number

[120-51-4]

Product Name Alternative

Phenylmethyl benzoate

UNSPSC

12352005

Hazard Statement

H302+H312, H313, H315+H320, H317, H360, H373, H410

Target

Angiotensin Receptor; Bacterial; Endogenous Metabolite; Fungal; Parasite

Type

Natural Products

Related Pathways

Anti-infection; GPCR/G Protein; Metabolic Enzyme/Protease

Applications

Neuroscience-Neuromodulation

Field of Research

Infection; Inflammation/Immunology; Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/Benzyl-benzoate.html

Purity

99.98

Solubility

DMSO : 200 mg/mL (ultrasonic)

Smiles

O=C(OCC1=CC=CC=C1)C2=CC=CC=C2

Molecular Formula

C14H12O2

Molecular Weight

212.25

Precautions

H302+H312, H313, H315+H320, H317, H360, H373, H410

References & Citations

[2]Raynaud S, et al. Squamocin and benzyl benzoate, acaricidal components of Uvaria pauci-ovulata bark extracts. Planta Med. 2000 Mar;66 (2) :173-5. |[3]Acar A, et al. Investigation of benzyl benzoate toxicity with anatomical, physiological, cytogenetic and biochemical parameters in in vivo[J]. Caryologia, 2020, 73 (3) .|[4]Kılıç Süloğlu A, et al. Toxicity of benzyl benzoate as a food additive and pharmaceutical agent. Toxicol Ind Health. 2022 Apr;38 (4) :221-233. |[5]Ohno O, et al. Inhibitory effects of benzyl benzoate and its derivatives on angiotensin II-induced hypertension. Bioorg Med Chem. 2008 Aug 15;16 (16) :7843-52. |[1]Bachewar NP, et al. Comparison of safety, efficacy, and cost effectiveness of benzyl benzoate, permethrin, and ivermectin in patients of scabies. Indian J Pharmacol. 2009 Feb;41 (1) :9-14.