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Clemastine (fumarate) (Standard)

Clemastine (fumarate) (Standard) is the analytical standard of Clemastine (fumarate) . This product is intended for research and analytical applications. Clemastine (HS-592) fumarate is a selective histamine H1 receptor antagonist. Clemastine fumarate is an antihistamine mainly used for relieving symptoms of allergic reactions primarily by competing with histamine to bind H1 receptors. Anti-inflammatory effects[1][2].

Product Specifications

CAS Number

14976-57-9

Product Name Alternative

HS-592 (fumarate) (Standard) ; Meclastine (fumarate) (Standard)

UNSPSC

12352005

Target

Histamine Receptor; Reference Standards

Type

Reference Standards

Related Pathways

GPCR/G Protein; Immunology/Inflammation; Neuronal Signaling; Others

Field of Research

Neurological Disease; Endocrinology

Assay Protocol

https://www.medchemexpress.com/clemastine-fumarate-standard.html

Smiles

CN1[C@@H](CCO[C@](C2=CC=CC=C2)(C3=CC=C(Cl)C=C3)C)CCC1.O=C(O)/C=C/C(O)=O

Molecular Formula

C25H30ClNO5

Molecular Weight

459.96

References & Citations

[1]Seifert, R., et al., Histamine increases cytosolic Ca2+ in dibutyryl-cAMP-differentiated HL-60 cells via H1 receptors and is an incomplete secretagogue. Mol Pharmacol, 1992. 42 (2) : p. 227-34.|[2]Clemastine. In: LiverTox: Clinical and Research Information on Drug-Induced Liver Injury. Bethesda (MD) : National Institute of Diabetes and Digestive and Kidney Diseases; January 16, 2017.

Shipping Conditions

Room temperature

Scientific Category

Reference Standards

Clinical Information

Launched

Available Sizes

Frequently Asked Questions

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