CU-CPT17e
CU-CPT17e is a potent multi-Toll-like receptor (TLR) agonist that activates TLR3, TLR8, and TLR9.
Product Specifications
CAS Number
2109805-75-4
UNSPSC
12352005
Hazard Statement
H228, H315, H319
Target
Toll-like Receptor (TLR)
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
Cancer-programmed cell death
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/CU-CPT17e.html
Purity
99.00
Solubility
DMSO : 5 mg/mL (ultrasonic; warming)
Smiles
O=[N+]([O-])C(C=C1)=CC=C1COC2=CC(C=CC3(CCOCC3)O4)=C4C=C2OCC5=CC=C([N+]([O-])=O)C=C5
Molecular Formula
C27H24N2O8
Molecular Weight
504.49
Precautions
H228, H315, H319
References & Citations
[1]Zhang L, et al. Discovery of Small Molecules as Multi-Toll-like Receptor Agonists with Proinflammatory and Anticancer Activities. J Med Chem. 2017 Jun 22;60 (12) :5029-5044.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
TLR3; TLR8; TLR9
Available Sizes
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