Isovalerylcarnitine
Isovalerylcarnitine is a product of the catabolism of L-leucine. Isovalerylcarnitine is also a selective and reversible calpain activator that induces apoptosis[1][2][3].
Product Specifications
CAS Number
31023-24-2
UNSPSC
12352211
Target
Endogenous Metabolite; Proteasome
Type
Natural Products
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/Isovalerylcarnitine.html
Purity
99.9
Solubility
DMSO : 150 mg/mL (ultrasonic)
Smiles
CC(C)CC(O[C@H](CC([O-])=O)C[N+](C)(C)C)=O
Molecular Formula
C12H23NO4
Molecular Weight
245.32
References & Citations
[1]Pontremoli S, et al. Isovalerylcarnitine is a specific activator of calpain of human neutrophils. Biochem Biophys Res Commun. 1987 Nov 13;148 (3) :1189-95.|[2]Ferrara F, et al. Evaluation of carnitine, acetylcarnitine and isovalerylcarnitine on immune function and apoptosis. Drugs Exp Clin Res. 2005;31 (3) :109-14. |[3]Pontremoli S, et al. Isovalerylcarnitine is a specific activator of the high calcium requiring calpain forms. Biochem Biophys Res Commun. 1990 Feb 28;167 (1) :373-80.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
Human Endogenous Metabolite
Available Sizes
Frequently Asked Questions
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