Cefcapene pivoxil (hydrochloride)

Cefcapene pivoxil hydrochloride, the pivalate ester prodrug form of Cefcapene, is an orally active third-generation cephalosporin with a wide spectrum of anti-bacterial activity. Cefcapene pivoxil hydrochloride has the potential for the palmoplantar pustulosis (PPP) research[1][2].

Product Specifications

CAS Number

[147816-23-7]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Antibiotic; Bacterial

Type

Reference compound

Related Pathways

Anti-infection

Applications

Neuroscience-Neuromodulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/cefcapene-pivoxil-hydrochloride.html

Purity

99.05

Solubility

DMSO : 125 mg/mL (ultrasonic) |H2O : < 0.1 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

[H]Cl.CC(C)(C)C(OCOC(C1=C(COC(N)=O)CS[C@@]([C@@H]2NC(/C(C3=CSC(N)=N3)=C\CC)=O)([H])N1C2=O)=O)=O

Molecular Formula

C23H30ClN5O8S2

Molecular Weight

604.10

Precautions

H302, H315, H319, H335

References & Citations

[1]Murakami M, et al. Cefcapene Pivoxil Hydrochloride Is a Potentially New Treatment for Palmoplantar Pustulosis with Pustulotic Arthro-Osteitis.Dermatology. 2015;231 (4) :304-11.|[2]Koh Okamoto, et al. Poor penetration of cefcapene into aqueous humor after oral administration of cefcapene pivoxil to patients undergoing cataract surgery. J Infect Chemother. 2020 Feb;26 (2) :312-315. |[3]Sekiya Y, et al. Comparative efficacies of different antibiotic treatments to eradicate nontypeable Haemophilus influenzae infection.BMC Infect Dis. 2008 Feb 7;8:15.