Hypaphorine
Hypaphorine is an indole found in Caragana korshinskii. Hypaphorine has neurological and glucose-lowering effects. Hypaphorine prevents Lipopolysaccharides (LPS) (HY-D1056) -mediated acute lung injury (ALI) and proinflammatory response via inactivating the p38/JNK signaling pathway by upregulating DUSP1[1][2][3][4].
Product Specifications
CAS Number
[487-58-1]
UNSPSC
12352005
Hazard Statement
H301, H311, H331
Target
JNK; p38 MAPK
Type
Natural Products
Related Pathways
MAPK/ERK Pathway
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease; Inflammation/Immunology; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/hypaphorine.html
Purity
99.93
Solubility
DMSO : < 1 mg/mL (ultrasonic; warming; heat to 60°C) |H2O : 100 mg/mL (ultrasonic)
Smiles
C[N+](C)(C)[C@H](C([O-])=O)CC1=CNC2=CC=CC=C12
Molecular Formula
C14H18N2O2
Molecular Weight
246.31
Precautions
H301, H311, H331
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-N2179/Hypaphorine-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-N2179/Hypaphorine-SDS-MedChemExpress.pdf
Scientific Category
Natural Products
Clinical Information
No Development Reported
Available Sizes
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