CD2314

CD2314 is a potent and selective RARβ receptor agonist with a Kd of 195 nM in S91 melanoma cells[1].

Product Specifications

CAS Number

[170355-37-0]

UNSPSC

12352005

Target

RAR/RXR

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/cd2314.html

Concentration

10mM

Purity

99.84

Solubility

DMSO : 83.33 mg/mL (ultrasonic)

Smiles

O=C(C1=CSC(C2=CC=C3C=C4C(C)(C)CCC(C)(C)C4=CC3=C2)=C1)O

Molecular Formula

C23H24O2S

Molecular Weight

364.50

References & Citations

[1]Spanjaard RA, et al. Specific activation of retinoic acid receptors (RARs) and retinoid X receptors reveals a unique role for RARgamma in induction of differentiation and apoptosis of S91 melanoma cells. J Biol Chem. 1997 Jul 25;272 (30) :18990-9.